Objective To investigate feasibility of bowel preparation for colonoscopy in endoscopic ambulatory surgery ward. Methods, A total of 352 patients at endoscopic ambulatory surgery ward receiving colonoscopy at Zhongshan Hospital Fudan University from May 25, 2018 to July 13, 2018 were surveyed by questionnaires. Data of 344 patients, including patient demographics, bowel preparation information and Boston bowel preparation scores and subjective perception of patients, were analyzed, and data of 8 others were excluded because they did not complete colonoscopy for the first time due to failure of bowel preparation. Chi-square test and logistic regression analysis were conducted to analyze the quality of bowel preparation and its influencing factors. Results A total of 18.0%(62/344) of bowel preparations were inadequate. Morning colonoscopy (P=0.005，OR=2.505，95%CI：1.312-4.781) and yellow residual last stool before colonoscopy (P=0.045，OR=0.475，95%CI：0.230-0.982) were independent risk factors for inadequate bowel preparation. Patients’ tolerance was 88.1%(303/344), satisfaction was 77.9%(268/344), and 54.9%(189/344) were willing to be hospitalized in ambulatory surgery ward again if necessary. Conclusion Bowel preparation before colonoscopy in endoscopic ambulatory surgery ward is feasible but not optimal.