Linked color imaging (LCI) was a novel image-enhanced endoscopic technology, which has been gradually applied in clinical practice. Several studies have verified that LCI could improve the endoscopic diagnostic accuracy for gastrointestinal mucosal lesions via increasing the contrast between abnormal and normal mucosa. Although the value of LCI in clinical application has already been widely acknowledged by clinicians both at home and abroad, there are still some problems like the improper usage of LCI and the unclear definition of certain LCI terms, which hinders the further clinical application and related research on LCI. Thus, this issue was discussed together by famous experts on gastrointestinal endoscopy in China, and the main points were summarized and written following related clinical guidelines in this field according to the recent research and clinical evidence on the LCI diagnosis for gastrointestinal lesions.