内镜黏膜下剥离术治疗下咽早期癌及癌前病变的临床价值(含视频)
作者:
作者单位:

四川省肿瘤医院内镜诊治部

作者简介:

通讯作者:

中图分类号:

基金项目:

国家重点研发计划(2016YFC1303601)


Endoscopic submucosal dissection for superficial hypopharyngeal carcinomas (with video)
Author:
Affiliation:

Sichuan Cancer Hospital

Fund Project:

Hypopharyngeal neoplasms;Nasopharyngeal carcinoma;Endoscopic submucosal dissection

  • 摘要
  • |
  • 图/表
  • |
  • 访问统计
  • |
  • 参考文献
  • |
  • 相似文献
  • |
  • 引证文献
  • |
  • 文章评论
    摘要:

    目的探讨内镜黏膜下剥离术(endoscopic submucosal dissection,ESD)治疗下咽早期癌及癌前病变的有效性及安全性。方法回顾性分析2015年12月—2019年5月在四川省肿瘤医院接受ESD的23例下咽早期癌及癌前病变患者的临床资料。结果23例患者共30处病灶纳入研究,患者均为男性,平均年龄60.3岁(47~72岁)。23例患者中,13例伴同时性食管癌,3例伴异时性食管癌,7例伴同时性食管高级别上皮内瘤变。患者均成功完成ESD,平均手术时间74 min,整块切除率100%。术后病理提示21处为高级别上皮内瘤变、8处为黏膜内癌、1处为黏膜下深浸润癌。水平切缘阳性2例,垂直切缘阳性1例,治愈性切除率90%。术中及术后无严重出血、穿孔、呼吸困难等并发症。结论ESD治疗下咽早期癌及癌前病变安全可行,值得在临床中推广应用。

    Abstract:

    ObjectiveTo evaluate the efficacy and safety of endoscopic submucosal dissection(ESD) for early hypopharyngeal carcinoma and precancerous lesions. MethodsData of 23 patients with early hypopharyngeal carcinoma and precancerous lesions who underwent ESD in Sichuan Cancer Hospital from December 2015 to May 2019 were analyzed. ResultsA total of 23 patients with 30 lesions were enrolled in the study. All patients were male, with mean age of 60.3 years (ranged 47-72). Of the 23 patients, 13 had synchronous esophageal cancer, 3 had metachronous esophageal cancer, and 7 high-grade intraepithelial neoplasia(HGIN) of the esophagus. The mean procedure time was 74 minutes. The en bloc resection rate was 100%. Pathological results revealed that 21 lesions were HGIN, 8 lesions were intramucosal carcinoma and 1 lesion had tumor invasion of the submucosa. Two patients had positive horizontal margin and 1 patient had positive vertical margin. The curative resection rate was 90%. No bleeding, perforation or dyspnea occurred during or after ESD. ConclusionsESD is safe and effective for early hypopharyngeal cancer and precancerous lesions.

    参考文献
    相似文献
    引证文献
引用本文

赵锐,包郁,周凌霄,等.内镜黏膜下剥离术治疗下咽早期癌及癌前病变的临床价值(含视频)[J].中华消化内镜杂志,2020,37(7):495-498.

复制
分享
文章指标
  • 点击次数:
  • 下载次数:
  • HTML阅读次数:
  • 引用次数:
历史
  • 收稿日期:2019-09-03
  • 最后修改日期:2020-05-08
  • 录用日期:2019-10-24
  • 在线发布日期: 2020-07-29
  • 出版日期:
您是第位访问者

通信地址:南京市鼓楼区紫竹林3号《中华消化内镜杂志》编辑部   邮编:210003

中华消化内镜杂志 ® 2024 版权所有
技术支持:北京勤云科技发展有限公司