胃增生性息肉伴癌变的临床病理特征分析
作者:
作者单位:

1.南京医科大学鼓楼临床医学院消化科;2.北京友谊医院病理科

作者简介:

通讯作者:

中图分类号:

基金项目:

国家重点研发计划(2016YFC1303600)


Clinical and pathological characteristics of gastric hyperplastic polyps coexisting with gastric cancers
Author:
Affiliation:

Department of Gastroenterology, Nanjing Drum Tower Hospital, Clinical College of Nanjing Medical School

Fund Project:

National Key Research and Development Program of China (2016YFC1303600)

  • 摘要
  • |
  • 图/表
  • |
  • 访问统计
  • |
  • 参考文献
  • |
  • 相似文献
  • |
  • 引证文献
  • |
  • 文章评论
    摘要:

    目的探讨胃增生性息肉(gastric hyperplastic polyps,GHP)伴癌变的临床、内镜和病理特点。方法对18例病理确诊为GHP伴癌变患者的临床表现、内镜特征、病理特点、治疗情况进行回顾性分析。结果18例GHP伴癌变患者年龄(67.2±7.8)岁(45~79岁),男6例、女12例;临床症状表现为腹痛、腹胀或无明显症状。患者合并胃内多发息肉为主(13例),单发的癌变GHP好发部位在胃体(7例)。内镜下病灶形态多样,15例为带蒂息肉,癌变息肉直径均>10 mm,9例直径>20 mm。背景黏膜中14例存在萎缩性胃炎,4例合并幽门螺杆菌(Helicobacter pylori,HP)感染。结论GHP伴癌变患者缺乏特异性症状,对于HP阴性合并萎缩性胃炎的多发性胃息肉患者,需警惕较大、带蒂息肉癌变的可能。

    Abstract:

    ObjectiveTo investigate the clinical,endoscopic and pathologic characteristics of gastric hyperplastic polyps coexisting with gastric cancers. MethodsA retrospective study was performed involving 18 patients who were pathologically confirmed with gastric hyperplastic polyps coexisting with gastric cancers. The clinical features, endoscopic findings, pathological characteristics and treatment strategy were analyzed. ResultsThe age of 18 patients was 67. 2±7. 8 years (ranged 45-79), including 6 males and 12 females. The symptoms included abdominal pain, distention, and some patients were asymptomatic. Multiple polyps (13/18) were common. Single lesions were often located in the gastric corpus (7/18). Endoscopy showed various morphological changes. Pedunculated polyp was the most common type (15/18). All polyps were larger than 10 mm in diameter, and the polyps in 9 patients were larger than 20 mm. Fourteen patients had atrophic gastritis in the background mucosa, and 4 patients had Helicobacter pylori (HP) infection. ConclusionGastric hyperplastic polyps coexisting with gastric cancers shows no specific symptoms. For HP (-) atrophic gastritis patients accompanied with multiple gastric polyps, malignant transformation of those larger and pedunculated polyps is of possibility.

    参考文献
    相似文献
    引证文献
引用本文

秦睿璐,徐桂芳,黄静雯,等.胃增生性息肉伴癌变的临床病理特征分析[J].中华消化内镜杂志,2020,37(7):487-490.

复制
分享
文章指标
  • 点击次数:
  • 下载次数:
  • HTML阅读次数:
  • 引用次数:
历史
  • 收稿日期:2019-11-01
  • 最后修改日期:2020-06-02
  • 录用日期:2019-12-23
  • 在线发布日期: 2020-07-29
  • 出版日期:
您是第位访问者

通信地址:南京市鼓楼区紫竹林3号《中华消化内镜杂志》编辑部   邮编:210003

中华消化内镜杂志 ® 2024 版权所有
技术支持:北京勤云科技发展有限公司