ObjectiveTo compare the difference between modified peroral endoscopic myotomy（Liu-POEM） and conventional POEM for achalasia. MethodsThirty achalasia patients treated with Liu-POEM and 30 with conventional POEM were enrolled. A retrospective study was performed to compare the conventional POEM and Liu-POEM procedures by evaluating total operation time， postoperative complications and symptoms（Eckardt score）. ResultsThe average total operation time of Liu-POEM was 27.13 ±11.42 min and the average myotomy time was 13.20±5.09 min. There was no pneumomediastinum， subcutaneous emphysema or fever. The average total operation time of conventional POEM was 51.22±25.63 min. The average myotomy time was 11.18±7.61 min. There were three cases（10％） of subcutaneous emphysema but recovered after two days without any special treatment. One patient who underwent conventional POEM had fever（the highest temperature was 37.6℃）and his temperature subsided to normal after physical cooling in one day. Postoperative Eckardt scores of patients were all less than 3. After postoperative follow-up of 3 to 12 months， no complications occurred in any patient. ConclusionLiu-POEM is a modified approach to treat achalasia， advantageous over conventional POEM in more simplified operation procedure， shorter operation time and less invasiveness.