Abstract:Objective To evaluate the efficacy and safety of endoscopy in the treatment of biliary anastomotic strictures. Methods Patients who received endoscopic treatment for benign biliary anastomotic strictures in Shanghai Changhai Hospital from January 2016 to January 2024 were included. According to the exclusion criteria, 53 cases were included in the final retrospective analysis, which mainly observed the endoscopic treatment methods, the number of interventions, the technical success rate, the recurrence time of biliary anastomotic strictures, the rate of recurrence and the occurrence of complications. Results A total of 103 endoscopic treatments were performed on 53 patients, with a technical success rate of 98.1% (101/103). Treatment modalities included stent placement combined with dilation in 48 cases (47.5%), stent placement alone in 40 cases (39.6%), and dilation alone in 13 cases (12.9%). During a median follow-up of 31.0 (13.5,50.3) months, 6 patients were excluded from the analysis due to death before the follow-up period was completed; 37 cases (78.7%) showed alleviation of biliary-enteric anastomotic stricture; 10 cases (21.3%) experienced recurrence of biliary-enteric anastomotic stricture. On average, patients with anastomotic strictures required another endoscopic intervention approximately every 6.2 (3.5,7.9) months, with a median of 1 (1,2) endoscopic interventions needed for stricture resolution. The overall complication rate was 12.9% (13/101), with surgery-related complications occurring in 7.9% (8/101) and stent-related complications in 5.0% (5/101) of the cases. Conclusion Endoscopic treatment is an important conservative treatment method for anastomosis strictures, with a high rate of stricture resolution and manageable complications.