真实世界无蒂结直肠息肉切除技术选择的单中心回顾性分析
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1.中国医学科学院北京协和医学院北京协和医院消化内科;2.中国医学科学院北京协和医学院群医学及公共卫生学院;3.中国医学科学院北京协和医学院 北京协和医院消化内科

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国家自然科学基金(No: 32370946)


A Real-world Single-center Retrospective Analysis of Technique Options for Nonpedunculated Colorectal Polypectomy
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1.Peking Union Medical College Hospital, Chinese Academy of Medical Sciences &2.amp;3.Peking Union Medical College

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National Natural Science Foundation of China (No: 32370946)

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    摘要:

    目的 分析不同长径的无蒂结直肠息肉使用冷活检钳息肉切除术(cold forcep polypectomy,CFP)、冷圈套器息肉切除术(cold snare polypectomy,CSP)或内镜黏膜切除术(endoscopic mucosal resection,EMR)的真实世界情况。方法 回顾性纳入2022年1月至2023年12月北京协和医院消化内科切除的长径≤19 mm无蒂结直肠息肉12 290个(10 295例患者),由30名消化内科内镜医师完成息肉切除术。根据息肉长径分为1~5 mm、>5~10 mm及>10~19 mm三组,比较各组内切除方式的差异。在长径>5~10 mm组的息肉中,分析行CSP者金属夹使用情况及2022年与2023年>5~10 mm息肉切除方式的变化。结果 1~5 mm无蒂息肉(8 289个)以CFP切除(6 769个,81.7%)为主;>5~10 mm息肉(2 455个)切除以CSP(1 372个,55.9%)为主,但不同医师之间CSP使用率的差异较大,CSP中位使用率为52.9%(40.3%,60.0%)。>10~19 mm无蒂息肉(1 546个)以EMR切除(1 349个,87.3%)为主。2023年>5~10 mm无蒂息肉切除中CSP使用率64.2%(869/1354)较2022年45.7%(503/1101)明显升高。>5~10 mm无蒂息肉CSP中金属夹总体使用率为40.1%(550/1372),在不同医师之间有较大差异,中位使用率48.3%(29.8%,67.9%)。结论 内镜医师对于长径≤19 mm无蒂息肉的切除方法存在较大差异,1~5 mm息肉主要采用CFP,>5~10 mm息肉以CSP为主且使用率逐年增加,>10~19 mm息肉则主要采用EMR。CSP中金属夹使用率在不同医师间存在显著差异。

    Abstract:

    Objective This study aimed to retrospectively analyze the real-world practices of resecting colorectal polyps of varying sizes using cold forcep polypectomy (CFP), cold snare polypectomy (CSP), and endoscopic mucosal resection (EMR). Methods A total of 12,290 nonpedunculated colorectal polyps measuring ≤ 19 mm in length (from 10,295 patients) were enrolled from January 2022 to December 2023. Polypectomy was conducted by 30 endoscopists. The polyps were categorized into three groups based on size: 1~5 mm, >5~10 mm and >10~19 mm, to compare the polypectomy methods utilized in each group. The subgroup analysis was performed to examine the use of hemostatic clips in CSP for >5~10 mm polyps and the changes in resection methods between 2022 and 2023. Results CFP (6,769 polyps, 81.7%) was the predominant method for resecting 1~5 mm sessile polyps (8,289 polyps). For polyps sized >5~10 mm (2,455 polyps), CSP was used most frequently (1,372, 55.9%), although its utilization varied significantly among physicians (median 52.9%, quartile 40.3%, 60.0%). EMR (1,349 poolyps, 87.3%) was the main technique for >10~19 mm sessile polyps. The rate of CSP usage in nonpedunculated polypectomy for polyps larger than 5 to 10 mm significantly increased from 45.7% (503/1101) in 2022 to 64.2% (869/1354) in 2023. The frequency of using clip in CSP for >5~10 mm sessile polyps was 40.1% (550/1372) overall, demonstrating notable variability among different endoscopists (median 48.3%, quartile 29.8, 67.9%). Conclusion Significant differences exist in the resection methods for sessile polyps measuring ≤ 19 mm among endoscopists. CFP is primarily utilized for polyps between 1 and 5 mm. For polyps ranging from >5 to 10 mm, CSP is predominantly employed, with its annually usage rate increasing. In the case of polyps larger than 10 mm and up to 19 mm, EMR is the main approach. Additionally, notable variations in the use of metal clips during CSP are observed among different physicians.

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邓影南,丁晗玥,张晟瑜,等.真实世界无蒂结直肠息肉切除技术选择的单中心回顾性分析[J].中华消化内镜杂志,,().

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  • 收稿日期:2024-10-23
  • 最后修改日期:2025-04-27
  • 录用日期:2025-01-09
  • 在线发布日期: 2025-04-28
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