To investigate the efficacy and safety of endoscopic ultrasound (EUS)-guided coil combined with glue for the embolization of visceral arterial pseudoaneurysms (VAPA), we retrospectively analyzed the clinical data of 4 patients who underwent this procedure at the Endoscopy Center of Qilu Hospital, Shandong University between June 2024 and March 2025. Parameters including technical success rate, procedure duration, postoperative complications, costs, and postoperative hospital stay were recorded. The technical success rate was 100%, with embolization durations ranging from 1 minute 40 seconds to 4 minutes 20 seconds. No severe complications occurred in any patients. The procedure costs varied between 7,600 and 13,600 RMB, with postoperative hospitalization lasting 2-3 days. Notably, one patient underwent simultaneous endoscopic retrograde cholangiopancreatography (ERCP) for biliary and pancreatic stent replacement after successful embolization of VAPA while another received EUS-guided pancreatic pseudocyst drainage post-embolization. During follow-up periods of 2.0-11.0 months, no VAPA recurrence was observed in any case. This preliminary study demonstrates that EUS-guided coil combined with glue may represent a feasible and safe novel therapeutic approach for VAPA. Its advantages of being radiation-free, minimally invasive, time-efficient, and cost-effective warrant further clinical validation and application.