【Abstract】 Objective：Assess the application value of the intelligent endoscope transportation system in the digestive endoscopy center. Methods：A parallel-group controlled trial was conducted, with the robotic intelligent endoscope transport system as the experimental group and traditional manual transport as the control group. The study was carried out in the outpatient area of the Digestive Endoscopy Center at Qilu Hospital of Shandong University from June 1 to December 31, 2024. Performance metrics, including system response time, endoscope transport speed, and labor cost efficiency, were statistically analyzed. Full-time equivalent (FTE) was introduced to quantify the operational efficiency of the experimental group. Additionally, the two groups were compared in terms of contamination prevention, closed-loop traceability, and nursing staff satisfaction. Results: The study included a total of 60,206 instances of intelligent endoscope transportation and 60,485 instances of manual transportation data. The response time of the robotic group was （51.08±14.97） second, significantly shorter than the （54.44±13.61） second of the manual group, with a statistically significant difference（t=35.8，P<0.001）. The recovery response time of the robotic group was also （32.52±11.26） second, markedly shorter than the manual group’s （40.20±11.40） second, with a statistically significant difference（t=103.93，P<0.001） as well. During the 148-day operational period, the robotic group successfully transported 60,104 times, with 102 failures, resulting in a success rate of 99.83%（60 104/60 206）, and a failure rate of 0.17%（102/60 206）. The primary causes of failure were disconnection of the robot"s wireless network, failure in pathfinding, and robot malfunction, with an average of 1.05 malfunctions per month, and no adverse events occurred. During the same time period, the manual group successfully transported 60,043 cases and failed 442 times, resulting in a success rate of 99.26%（60 043/60 485）and a failure rate of 0.74%（442/60 485）. The satisfaction score for the endoscopic transport by the robotic group was rated at （4.65±0.55）points, which is significantly higher than the （3.97±0.98） points of the manual group, with a statistically significant difference（t=96.5，P<0.001）. Additionally, the satisfaction score for the transport process in the robotic group was also rated at （4.71±0.59） points, noticeably exceeding the manual group"s （3.90±1.04） points, with a statistically significant difference（t=210.3，P<0.001）. Furthermore, the score regarding workload intensity in the robotic group was rated at （4.06±0.77） points, which is significantly lower than the manual group"s score of （4.48±0.63） points, with a statistically significant difference（t=59.9，P=0.025）. Calculations indicate that utilizing the robotic intelligent endoscopic transport system can save 3.68 full-time equivalent positions, resulting in an approximate annual saving of 657，000 yuan in nursing labor costs. Conclusion The robotic intelligent endoscope transport system improves work efficiency, reduces nursing labor costs and physical workload, enhances job satisfaction, and enables full-process smart traceability, providing a scientific basis for process supervision and outcome management. It is a safe, effective, and widely applicable solution for endoscope transportation in digestive endoscopy centers.